OBJECTIVE: This meta-analysis study analyzed the effect of foot reflexology on fatigue in hemodialysis patients by combining the results of independent studies on this subject. METHOD: Meta-analysis study. A literature search was conducted in seven databases. The methodological quality of the included studies was assessed using tools proposed by the Joanna Briggs Institute. Comprehensive Meta-Analysis v3 was used for meta-analysis. RESULTS: Eight studies were included in the meta-analysis. The result of the meta-analysis standardized mean difference 1.580 (95% confidence interval 1.075 to 2.085 p = 0.000). The result of the subgroup analysis performed based on the number of foot reflexology sessions standardized mean difference 1,478 (95% confidence interval 1,210 to 1,747, p = 0.000). CONCLUSION: It was concluded that foot reflexology can be used to reduce fatigue in hemodialysis patients. No information was provided in the investigated studies about the possible side effects and negative effects of foot reflexology.

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