BACKGROUND: Brain tumor surgery poses significant challenges to patients, often resulting in neurological deficits that impact functional outcomes. Virtual Reality Neurorehabilitation (VRN) has emerged as a promising intervention to enhance recovery. This study aims to provide pathological insights into the impact of VRN on functional recovery after brain tumor surgery. AIMS: The primary objective was to investigate the effectiveness of VRN in promoting functional recovery by examining its influence on neurological pathways post-surgery. MATERIALS AND METHODS: A prospective cohort study was conducted involving patients undergoing brain tumor surgery. Participants were randomized into two groups: one receiving standard postoperative care, and the other undergoing VRN-based neurorehabilitation. Preoperative and postoperative neurological assessments, including imaging studies and standardized functional outcome measures, were employed to evaluate the impact of VRN. The VRN interventions were involve immersive exercises designed to target specific cognitive and motor functions affected by the surgery. Data analysis was include statistical comparisons between the two groups, considering variables such as neuroimaging findings, functional scores, and rehabilitation adherence. RESULTS: Preliminary results indicate that participants in the VRN group exhibit more favorable trends in terms of postoperative functional recovery compared to the control group. Neuroimaging reveals potential neuroplastic changes in key regions associated with motor and cognitive functions. Furthermore, participants in the VRN group demonstrate higher adherence to rehabilitation protocols. CONCLUSIONS: This study provides valuable pathological insights into the impact of VRN on functional recovery after brain tumor surgery. The preliminary results suggest that VRN may offer a novel and effective approach to neurorehabilitation, fostering neuroplasticity and improving functional outcomes. Further analysis and follow-up assessments are warranted to validate these findings and establish the long-term benefits of integrating VRN into postoperative care strategies.

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