OBJECTIVE: To report the treatment effects of early use Kinesiotaping on pain, range of motion, mobility, and edema outcomes following total knee arthroplasty. DATA SOURCES: Cochrane Central Register of Controlled Trials, PubMED, SPORTDiscus, Biosis Citation Index, and the Cumulative Index to Nursing and Allied Health Literature were searched for potential randomized control trials from inception to 8 January 2024. REVIEW METHODS: Randomized control trials evaluating the effect of Kinesiotaping published in English were included. Reference lists for relevant reviews were searched. Study quality was assessed using the Cochrane Risk of Bias 2 tool. Certainty of evidence was determined using the Grading of Recommendations Assessment, Development, and Evaluation approach. RESULTS: Seven articles totaling 534 participants were included for meta-analysis. Kinesiotaping with standard rehabilitation when compared to standard rehabilitation alone had very low certainty of evidence in pain and knee flexion range of motion. Kinesiotaping was favored at post-operative days two to four for pain (p = 0.03, standard mean difference -0.77 (-1.45 to -0.09)) and range of motion (p = 0.002, standard mean difference -0.24 (-0.44 to -0.03)). Kinesiotaping was favored at post-operative days six to eight for pain (p = 0.02, standard mean difference -0.76 (-1.41 to -0.12)) and range of motion (p = 0.04, standard mean difference -0.63 (-1.22 to -0.04)). Edema and mobility could not be meta-analyzed. CONCLUSION: The use of Kinesiotaping early in post-operative rehabilitation could be a useful modality for reducing pain and increasing the range of knee flexion, however, the certainty of evidence is very low.

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