Use the Back button in your browser to see the other results of your search or to select another record.

Detailed Search Results

Efficacy of specified manual therapies in combination with a supervised exercise protocol for managing pain intensity and functional disability in patients with knee osteoarthritis
Reza MK, Shaphe MA, Qasheesh M, Shah MN, Alghadir AH, Iqbal A
Journal of Pain Research 2021 Jan 26;14:127-138
clinical trial
8/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: No; Baseline comparability: Yes; Blind subjects: Yes; Blind therapists: No; Blind assessors: Yes; Adequate follow-up: Yes; Intention-to-treat analysis: Yes; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

PURPOSE: The current study aimed to determine the efficacy of specified manual therapies in combination with a supervised exercise protocol for managing pain intensity and functional disability in patients with knee osteoarthritis. METHODS: The study was based on a two-arm parallel-group randomized controlled trial design, including a total of 32 participants with knee osteoarthritis randomly divided into groups A and B. Group A received a supervised exercise protocol; however, group B received specified manual therapies in combination with a supervised exercise protocol. Pain and functional disability were measured with the numeric pain rating scale (NPRS) and the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), respectively. Data were collected at baseline (pre-intervention), 2 weeks, and 4 weeks post-intervention. To evaluate the efficacy of specific manual therapies with supervised exercise compared to supervised exercise alone, an unpaired t-test and repeated measures ANOVA were used to analyze the data, keeping the level of significance at p < 0.05. RESULTS: A significant (p < 0.05) mean difference (MD) was found within group A and group B for both outcomes when we compared their baseline scores with 2-week (group A, NPRS MD -1.56 and WOMAC MD 14.94; group B, NPRS MD 2.06 and WOMAC MD 22.19) and 4-week post-intervention scores (group A, NPRS MD 0.62 and WOMAC MD 6.75; group B, NPRS MD 0.75 and WOMAC MD 11.12). In addition, significant mean differences (p < 0.05) reported for both outcomes when we compared their scores between groups A and B at 2 weeks (MD NPRS 0.69; WOMAC 10.87) and 4 weeks post-intervention (MD NPRS 0.31; WOMAC 8.00). Furthermore, a post hoc Scheffe analysis for the outcomes NPRS and WOMAC revealed the superiority of group B over group A. CONCLUSION: The specified manual therapies, in combination with a supervised exercise protocol, were found to be more effective than a supervised exercise protocol alone for improving pain and functional disability in patients with knee osteoarthritis.

Full text (sometimes free) may be available at these link(s):      help