Nonpharmacological methods are used in the management of pain and Kinesiophobia following total knee arthroplasty. The aim of this double-blind randomized controlled trial was to examine the effect of foot reflexology on pain and Kinesiophobia in patients following total knee arthroplasty. A total of 40 patients (20 in the control group and 20 in the intervention group) were randomly assigned to either of two groups for the study. The intervention group was exposed to foot reflexology. Postoperative Visual Analog Scale scores decreased faster in the intervention group compared to the control group (F 80.417; p < 0.001; eta2 0.685). The Western Ontario and McMaster Universities Osteoarthritis Index scores decreased in the intervention group over time, while they increased in the control group (p < 0.05). While a gradual increase was observed in the Tampa Scale for Kinesiophobia scores in the control group, there was a decrease in the intervention group (F 84.860; p < 0.001; eta2 0.696). The amount of analgesics used was lower in the intervention group (p < 0.05). Foot reflexology can be applied as an effective and safe method to manage pain and Kinesiophobia in total knee arthroplasty patients.

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