OBJECTIVE: Effective therapeutic strategies are crucial for managing Genito-Pelvic Pain/Penetration Disorder (GPPPD), a condition presenting challenges for both patients and health care providers. This study aims to assess the effectiveness of an online Graded Motor Imagery program in alleviating pain intensity and improving sexual function in women diagnosed with GPPPD. METHODS: Eighty-seven women were randomly assigned to either an online Graded Motor Imagery group or a control group. The online Graded Motor Imagery protocol involved engaging participants in 2-week segments of left/right judgment exercises, mental simulation of movements, and gradual exposure therapy. After 6 weeks, we assessed pain intensity and sexual function. The control group gained access to the program upon study completion. RESULTS: The online Graded Motor Imagery group demonstrated a significant reduction in pain intensity, coupled with improvements in sexual function. Notably, participants with enhanced movement imagery abilities experienced greater improvements, while those with negative beliefs and thoughts regarding vaginal penetration showed lower sexual function scores. CONCLUSION: An online Graded Motor Imagery program is effective in alleviating the pain burden faced by women dealing with GPPPD.

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