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Laser therapy for pain of trigeminal neuralgia
Walker JB, Akhanjee LK, Cooney MM, Goldstein J, Tamayoshi S, Segal-Gidan F
The Clinical Journal of Pain 1987 Dec;3(4):183-187
clinical trial
4/10 [Eligibility criteria: No; Random allocation: Yes; Concealed allocation: No; Baseline comparability: Yes; Blind subjects: Yes; Blind therapists: No; Blind assessors: Yes; Adequate follow-up: No; Intention-to-treat analysis: No; Between-group comparisons: No; Point estimates and variability: No. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

Human subjects received irradiation of the skin overlying peripheral nerves with a helium-neon laser (1 mW, 632.5 nm, 20 Hz) for 20 s to each site. This treatment was accompanied by irradiation of the skin overlying painful facial areas for 30 to 90 s according to a predetermined protocol. Control subjects received placebo treatment by an apparatus that looked identical to the laser apparatus but emitted no radiation. Laser or placebo therapy was repeated 3 times a week for 10 weeks. Subjects in the experimental group exhibited a statistically significant reduction in the intensity of pain as measured by the visual analog scale (p < 0.002) and the number of painful episodes. These results, combined with previous research, indicate that laser therapy may provide relief from some kinds of chronic pain.

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