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The physiological impacts of the low- and moderate-volume-HIIT with or without nano-curcumin supplement in women in menopause with obesity
Dabidi Roshan V, Noorbakhsh S, Ziatabar Ahmadi SF, Nikseresht M, Raposo A
Advances in Public Health 2024 Aug 12;2024(5243088):1-14
clinical trial
This trial has not yet been rated.

Tabata exercise has been proposed as an extremely time-efficient high-intensity interval training (HIIT) method to achieve health benefits, but direct comparisons between the low-volume-HIIT (LV-HIIT), moderate-volume-HIIT (MV-HIIT) with and without nano-curcumin (NaC) supplement for 8-week on cardiovascular hemodynamic, respiratory function, muscular fitness, and physical performance in the obese menopause women are limited. In a double blind, randomized, placebo-controlled study, 53, moderately obese menopause women (average age 45 to 60 yrs, BMI > 30 kg/m 2, WC for > 85 cm, and body fat > 35%) were randomly assigned to undertake either LV-HIIT, MV-HIIT, or NaC supplement (daily 80 mg in two 40-mg capsules) for two sessions per week for 8 weeks. The maximal exercise testing after 8-week of the LV-HIIT and MV-HIIT interventions caused significantly increase in the VO2max (mean difference 6.83 (95% CI 25.58 to 43.51), p = 0.01, mean difference 5.31 (95% CI 23.98 to 39.02), p = 0.028), and oxygen pulse (mean difference 0.02 (95% CI 0.16 to 0.19), p = 0.04, mean difference 0.04 (95% CI 0.17 to 0.21), p = 0.02), respectively. Moreover, MV-HIIT with and without NaC had signi�cant improve in muscular fitness and physical performance (hand grip in MV plus NaC (mean difference 3.8 (95% CI 21.46 to 31.81), p = 0.02), quadriceps strength in MV (mean difference 14.58 (95% CI 52.75 to 69.82), p = 0.01), MQI (mean difference 31.23 (95% CI 112.67 to 197.15), p = 0.02, mean difference 31.52 (95% CI 159.13 to 184.07), p = 0.01), sit to stand test (mean difference 1.84 (95% CI 6.60 to 8.41), p = 0.02, mean difference 1.78 (95% CI 6.69 to 9.03), p = 0.01), and the running distance (mean difference 96.95 (95% CI 470.05 to 637.42), p = 0.02, mean difference 114.53 (95% CI 458 to 641.87), p = 0.02)), when compared to baseline. In compared with the LV-HIIT groups, the MV-HIIT could improve FVC (mean difference 0.12 (95% CI 2.21 to 3.26)). Our data demonstrated that both the LV-HIIT and MV-HIIT, as part of activities of daily living, maybe a time-efficient strategy to improve cardiorespiratory fitness and physical performance. Beyond the purported health bene�ts, the MV-HIIT with and without NaC supplement appears to be safe approach in the previously sedentary obese menopause women.

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