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| Relation of exercise to the recurrence rate of myocardial infarction in men. Ontario Exercise-Heart Collaborative Study |
| Rechnitzer PA, Cunningham DA, Andrew GM, Buck CW, Jones NL, Kavanagh T, Oldridge NB, Parker JO, Shephard RJ, Sutton JR, Donner AP |
| The American Journal of Cardiology 1983 Jan 1;51(1):65-69 |
| clinical trial |
| 5/10 [Eligibility criteria: No; Random allocation: Yes; Concealed allocation: No; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: Yes; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed* |
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The Ontario Exercise-Heart Collaborative Study was a multicenter randomized clinical trial of high intensity exercise for the prevention of recurrent myocardial infarction in men. The 4-year recurrence rate among 379 patients on a program of high intensity exercise did not differ significantly from that among 354 control patients on a program of light exercise, despite the greater reduction in heart rate in the former group. The relative odds of recurrence in the high intensity group were 1.09, with 95% confidence limits of 0.61 and 1.96.
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