PURPOSE: This Guideline covers the evaluation and treatment of men who present to a clinician with a complaint of chronic pelvic pain. The presentation of these men is widely variable. This variability in clinical presentations and multidisciplinary diagnostic and treatment considerations makes management challenging. This Guideline is intended for clinicians evaluating and managing male chronic pelvic pain. The following conditions are covered in this Guideline: (i) chronic prostatitis/ chronic pelvic pain syndrome (CP/CPPS), and (ii) chronic scrotal content pain (CSCP). METHODOLOGY: The systematic review that informs the Guideline statements was based on searches in Ovid MEDLINE (1946 to June 6, 2023), the Cochrane Central Register of Controlled Trials (through May 2023), and the Cochrane Database of Systematic Reviews (through May 2023). Searches were supplemented by reviewing electronic databases reference lists of relevant articles. Criteria for inclusion and exclusion of studies were based on the Key Questions and the PICOTS of interest. An updated search was conducted in June 2024 using the same criteria to bring in relevant literature published since the initial search.

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