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Effects of reducing sedentary behavior on liver insulin sensitivity, liver fat content, and liver enzyme levels: a six-month randomized controlled trial [with consumer summary]
Laine S, Sjoros T, Garthwaite T, Honka M-J, Loyttyniemi E, Norha J, Eskola O, Koivumaki M, Vaha-Ypya H, Sievanen H, Vasankari T, Hirvonen J, Laitinen K, Houttu N, Kalliokoski KK, Saunavaara V, Knuuti J, Heinonen IHA
American Journal of Physiology - Endocrinology and Metabolism 2025 Jun;328(6):E756-E771
clinical trial
6/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: No; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: Yes; Intention-to-treat analysis: Yes; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

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