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Does a real-life cognitively enriched walking program Take a Walk With Your Brain benefit cognitive functioning and physical activity in community-dwelling older adults? A randomized controlled trial
Hotterbeex P, Cardon G, Beeckman M, Latomme J, Fias W, van Puyenbroeck S, Chastin S, van Uffelen J
The Gerontologist 2025 May;65(6):gnaf043
clinical trial
This trial has not yet been rated.

BACKGROUND AND OBJECTIVES: Most studies examining combined cognitive and physical activity are conducted in laboratory settings. This randomized controlled trial (RCT) examines the effects of a real-life cognitively enriched walking program on cognitive functioning and moderate-to-vigorous physical activity (MVPA) in adults aged >= 65 years. RESEARCH DESIGN AND METHODS: A three-arm RCT was conducted, comparing the cognitively enriched walking program (WALK+, doing cognitive tasks while walking) with a walking program without enrichment (WALK-only) and a passive control condition (CONT). Both WALK+ and WALK-only had a duration of 6 months, with 2 outdoors, supervised group-based sessions per week (60 to 90 min/session). Cognitive functioning (short- and long-term memory, executive functioning, and processing speed) and MVPA were measured at baseline, 3, 6, and 12 months using the Cambridge Neuropsychological Test Automated Battery (CANTAB) and ActiGraph GT3X+ accelerometers, respectively. RESULTS: A total of 148 community-dwelling adults (median age 69 years, range 65 to 85; 72% (n = 107) female) were included. Comparing WALK+ to WALK-only and CONT, and WALK-only to CONT, there were no significant intervention effects on cognitive functioning at 3, 6, or 12 months. MVPA decreased with 13 min/day in WALK+ between baseline and 12 months, while it increased between baseline and 6 months with 12 min/day in WALK-only and between 3 and 6 months with 16 min/day in CONT. DISCUSSION AND IMPLICATIONS: The WALK+ program did not lead to statistically significant benefits for cognitive functioning or MVPA compared to WALK-only or CONT. Future studies should explore for whom combined interventions may work and determine the optimal dosage.
Copyright the Gerontological Society of America. Reproduced by permission of the publisher.

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