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The relationship between abdominal fat and sleep quality after combined exercise in patients with type 2 diabetes mellitus
Han Y, Han Y-X, Huang F, Zou H-M, Gu Q, Hu X, Fang J-X, Meng J, Wang S-J
Frontiers in Endocrinology 2025 Jun 27;16(1471608):Epub
clinical trial
This trial has not yet been rated.

BACKGROUND: Exercise holds promise as a non-pharmacological intervention for improving sleep quality. Therefore, this study investigated the potential relationship between abdominal fat and sleep quality after combined exercise in patients with T2DM (Type 2 diabetes mellitus). MATERIALS AND METHODS: A total of 100 adults with T2DM (52 women, 48 men), aged 55 to 75years, were enrolled in the study who were sufficiently active and physically fit were recruited and were randomized equally into four groups: a control group, an AEX group (aerobic exercise), a REX group (resistance exercise) and a COMB group (combination exercise). Patient sleep monitoring reports were collected using a smart bracelet. After 12 weeks of intervention, the Pittsburgh Sleep Quality Index (PSQI) total score, total sleep time, sleep efficiency, time to reawakening, BMI (body mass index), FBG (fasting blood glucose), HOMA-IR (insulin resistance index), HbA1c (glycosylated hemoglobin), VAT (visceral adipose tissue), SAT (subcutaneous adipose tissue), and LBM (lean body mass) were compared among the four groups. RESULTS: All exercise training programs improved the PSQI score in patients with type 2 diabetes. COMB is the only training that improves objective sleep quality and quantity, including total sleep time, sleep efficiency, and wake time after sleep onset. CONCLUSIONS: A comprehensive exercise program to reduce abdominal fat can benefit metabolic and sleep health in people with type 2 diabetes.

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