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Structured and specialized physical therapy: does it make a difference for children with congenital Zika syndrome? A pilot randomized controlled trial
Gama GL, Santino TA, Dos Santos Barros E, de Sales Tavares J, da Silva PJ, de Sales Regis T, de Sales Tavares J, Melo A
Developmental Neurorehabilitation 2025 Jul-Oct;28(6-7):231-237
clinical trial
This trial has not yet been rated.

Interventions for improving motor function of children with congenital Zika syndrome (CZS) are still underexplored. This study aimed to evaluate the feasibility of a structured and specialized 12-week intervention based on the Bobath concept and Pediasuit protocol compared to no change in therapeutic routine on the motor function of children with CZS. This pilot randomized controlled trial was conducted in a support center for children with microcephaly in Brazil between February and May 2018. Sixteen children were included. Anthropometric variables and motor functions (GMFM-88) were assessed. The experimental group (EG) underwent a one-hour daily protocol (30 min of motor physiotherapy based on Bobath concept and 30 min using therapeutic clothing). The control group kept their therapeutic routine. GMFM-88 total scores showed statistically significant improvement between assessments only for EG (p < 0.001). A structured and specialized 12-week physical therapy protocol is feasible and may improve children with CZS motor function.

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