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| Responders COPD patients to two different home-based rehabilitation programs: a blind, randomized, and controlled clinical trial [with consumer summary] |
| da Silva MMC, Ferreira Arcuri J, Viana DR, Marrara KT, Zorrer Franco FJB, de Souza NM, Bueno LG, de Oliveira BSV, Galhardo Rizzatti FP, Gibertoni LCF, Di Lorenzo VAP |
| Disability and Rehabilitation 2025;47(15):3897-3904 |
| clinical trial |
| This trial has not yet been rated. |
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PURPOSE: To verify the number of patients with COPD responders to two different home-based rehabilitation programs. METHODS: This was a blinded, randomized, and controlled clinical trial. The six-minute step test (6MST), one-minute sit-stand test (1-MSTST), six-minute walk test (6MWT), COPD Assessment Test (CAT), modified Medical Research Council (mMRC), monitoring of physical activity in daily life, and isometric quadriceps muscle strength were assessed pre- and post-intervention. A total of 50 patients were randomized into two groups: hybrid rehabilitation (HR), consisting of supervised physical exercise once a week associated with exercises at home, and home-based rehabilitation (HBR), which consisted of a single meeting for guidance related to the physical exercises prescribed. RESULTS: Significant differences (p < 0.05) were observed in the following parameters post-intervention and between groups: 6MST (HR 67.1 +/- 25.7 to 93.5 +/- 37.2; HBR 69.6 +/- 19.5 to 82.3 +/- 25.2 steps), 6MWT (HR 367.7 +/- 84 to 433.2 +/- 88.8; HBR 396.2 +/- 97.2 to 418.3 +/- 83.8 m), CAT (HR 19.5 +/- 6.8 to 13.0 +/- 7.8; HBR 17.0 +/- 7.6 to 15.0 +/- 10 points), and mMRC (HR 2 (2 to 3) to 1 (1 to 2); HBR 2 (2 to 3) to 2 (1 to 3) points). However, the response rate was 80% in the HR and 50% in the HBR. CONCLUSION: Both pulmonary rehabilitation programs improved physical capacity, alleviated dyspnea, and reduced the impact of the disease on health status; however, the number of responders was higher in the HR.
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