BACKGROUND: Knee osteoarthritis (KOA) negatively affects quality of life in older adults, leading to reduced mobility and psychological issues such as depression and anxiety. Taichi, a traditional mind-body practice, may offer therapeutic benefits for this population. METHODS: A structured Taichi intervention was implemented among older adults with KOA. Pre- and post-intervention assessments evaluated knee function, lower limb strength, balance, and psychological outcomes, including depression, anxiety, and stress. Paired t-tests were used to analyze changes. RESULTS: This study revealed that The Taichi group showed a statistically significant improvement in knee function (mean difference 21.6 points, 95% CI 17.3 to 25.9, p = 0.001, Cohen d 1.87), lower limb strength (mean difference 24.4 kg, 95% CI 16.5 to 32.2, p = 0.001, d 1.01), and balance (mean difference 12.6 points, 95% CI 2.8 to 22.3, p = 0.014, d 1.01). Psychological outcomes also improved significantly in the intervention group: depression (mean difference -2.70, 95% CI -3.71 to -1.69, p = 0.001, d 1.06), anxiety (mean difference -2.28, 95% CI -3.26 to -1.30, p = 0.001, d 0.75), and stress (mean difference -2.79, 95% CI -5.19 to -0.39, p = 0.025, d 0.61). CONCLUSION: These findings suggest Taichi as a non-pharmacological intervention for improving both physical and psychological outcomes in older adults with KOA. As a holistic mind-body therapy, Taichi presents a promising approach to enhancing functional ability and mental well-being in this population, reinforcing the concept that Taichi is Medicine.

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