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| Effects of low-volume high-intensity interval training on physical performance in older adults with possible sarcopenia: a randomized controlled trial |
| Wang Q, Xu C, Chen Y, Wang W, Xiao M, Chen H, Huang M |
| Archives of Physical Medicine and Rehabilitation 2025 May;107(5):1021-1030 |
| clinical trial |
| This trial has not yet been rated. |
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OBJECTIVE: To compare the effects of low-volume high-intensity interval training (HIIT) with moderate-intensity continuous training (MICT) on physical performance, muscle strength, and exercise enjoyment in older adults with possible sarcopenia. DESIGN: A two-arm, assessor-blind randomized controlled trial. SETTING: Community-based. PARTICIPANTS: Thirty older adults with possible sarcopenia (mean +/- SD age 66.0 +/- 3.7 years, 67% female). INTERVENTION: Participants were randomized to either a 15-minute HIIT protocol (5x1-minute cycling at 77% to 90% maximum heart rate (HRmax) or 15 to 17 ratings of perceived exertion (RPE) interspersed with 1-minute recovery; n = 15) or 25-minute MICT protocol (cycling at 65% to 76% HRmax or 12 to 14 RPE; n = 15), performed for 3 days per week for 7 weeks. MAIN OUTCOME MEASURES: The primary outcome was the five times sit to stand test. Secondary outcomes included comfortable walking speed, handgrip strength, and functional reach test. Exploratory outcomes were exercise enjoyment assessed using the Physical Activity Enjoyment Scale and the Exercise Enjoyment Scale. RESULTS: The HIIT group showed greater improvements in five times sit to stand test compared with the MICT group post-intervention (DELTA-0.57 s (95% CI -1.10 to -0.04), p = 0.04, eta2 0.15), at 1-month (DELTA-0.58 s (95% CI -1.13 to -0.04), p = 0.04, eta2 0.15), and 3-month follow-ups (DELTA-0.58 s (95% CI -1.13 to -0.02), p = 0.04, eta2 0.14). Both groups demonstrated significant improvements over time in five times sit to stand test time (p < 0.001, eta2 0.77), comfortable walking speed (p < 0.001, eta2 0.79), handgrip strength (p < 0.001, eta2 0.88) and functional reach test (p < 0.001, eta2 0.78). Participants in the HIIT group reported significantly higher scores on the Physical Activity Enjoyment Scale and the Exercise Enjoyment Scale compared with those in the MICT group. CONCLUSIONS: HIIT provides superior and sustained improvements in physical performance, as well as greater exercise enjoyment, over MICT in older adults with possible sarcopenia. CLINICAL TRIAL REGISTRATION: This study was registered at ClinicalTrials.gov under registration number NCT05790863.
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