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Relieving dyspnea with an inexpensive and simple method in patients with severe chronic airflow limitation
Falk P, Eriksen AM, Kolliker K, Andersen JB
European Journal of Respiratory Diseases 1985 Mar;66(3):181-186
clinical trial
8/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: No; Baseline comparability: Yes; Blind subjects: Yes; Blind therapists: No; Blind assessors: Yes; Adequate follow-up: Yes; Intention-to-treat analysis: Yes; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

The effect of inspiratory resistive breathing training using a simple apparatus was tested in 27 optimally medicated consecutive outpatients with severe chronic airflow limitation, randomly assigned to a test and a control group. Patients trained in their homes for up to 10 min thrice daily and increments in resistance were made, if possible, every fortnight. The control group used the same apparatus, but without inspiratory resistance. Three months from the start of training, the following statistically significant differences between the 2 groups were observed: a marked decrease in dyspnea in the trained group, a 60% versus 22% rise in endurance time on a cycle ergometer at 2/3 of maximal work load, a fall in functional residual capacity, and a fall in respiratory frequency both at rest and during exercise.
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