Detailed Search Results
| Author/Association: | Troosters T, Maltais F, Leidy N, Lavoie KL, Sedeno M, Janssens W, Garcia-Aymerich J, Erzen D, de Sousa D, Korducki L, Hamilton A, Bourbeau J |
| Title: | Effect of bronchodilation, exercise training, and behavior modification on symptoms and physical activity in chronic obstructive pulmonary disease [with consumer summary] |
| Source: | American Journal of Respiratory and Critical Care Medicine 2018 Oct 15;198(8):1021-1032 |
| Method: | clinical trial |
| Method Score: | 5/10 [Eligibility criteria: No; Random allocation: Yes; Concealed allocation: No; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: Yes; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed* |
| Consumer Summary: | AT A GLANCE COMMENTARY: SCIENTIFIC KNOWLEDGE ON THE SUBJECT: Chronic obstructive pulmonary disease (COPD) is associated with low levels of physical activity in daily life. Bronchodilation and exercise training (ExT) improve exercise tolerance in patients with COPD; however, behavior modification is required to impact daily physical activity. There is limited evidence on how a holistic approach to COPD treatment may affect improvements in exercise tolerance and physical activity. WHAT THIS STUDY ADDS TO THE FIELD: This is the first trial to examine the impact of a self-management behavior-modification (SMBM) program combined with bronchodilator therapy and ExT on exercise capacity and physical activity in patients with COPD. Tiotropium/olodaterol, with or without ExT, improved exercise endurance time in patients with COPD taking part in the SMBM program. Although SMBM alone was sufficient to increase physical activity, combination bronchodilation, alone or combined with ExT, was useful to reduce physical activity-related dyspnea and patient-reported difficulty. The combination of behavioral, exercise, and pharmacologic interventions resulted in the largest effect on physical activity experience and symptom improvement, a likely prerequisite for the long-term adoption of a more physically active lifestyle. |
| Abstract: | Copyright release for this abstract has not been granted. Abstract and full text (sometimes free) may be available at these link(s):  help |
