Detailed Search Results
Author/Association: | Jacob W, Dennis D, Jacques A, Marsh L, Woods P, Hebden-Todd T |
Title: | Ventilator hyperinflation determined by peak airway pressure delivered: a randomized crossover trial [with consumer summary] |
Source: | Nursing in Critical Care 2021 Jan;26(1):14-19 |
Method: | clinical trial |
Method Score: | 5/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: No; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: No; Intention-to-treat analysis: Yes; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed* |
Consumer Summary: | WHAT IS KNOWN ABOUT THIS TOPIC: Hyperinflation applied through external circuitry (manual hyperinflation, MHI) has been utilized in patients undergoing mechanical ventilation in the intensive care unit (ICU) since the early 1970's in order to facilitate lung secretion clearance and reverse atelectasis. The first study exploring hyperinflation applied within existing ventilator circuitry (ventilator hyperinflation, VHI) was published in 2002, with follow up reports suggesting widespread adoption of the technique in the ICU setting. Despite this uptake, few studies have described the manner with which it may be applied. WHAT THIS PAPER ADDS: This randomised crossover study applied a VHI protocol involving titration of hyperinflation according to airway pressure rather than lung volume, and compared sputum volumes produced with VHI and MHI. Results suggest that titration of airway volume according to airway pressure when delivering VHI yields greater wet weight of sputum and is safe. The approach requires a high-level dynamic understanding of ventilation principles. |
Abstract: | Copyright release for this abstract has not been granted. Abstract and full text (sometimes free) may be available at these link(s): ![]() |