Detailed Search Results
| Author/Association: | Messier SP, Newman JJ, Scarlett MJ, Mihalko SL, Miller GD, Nicklas BJ, DeVita P, Hunter DJ, Lyles MF, Eckstein F, Guermazi A, Loeser RF, Beavers DP |
| Title: | Changes in body weight and knee pain in adults with knee osteoarthritis three-and-a-half years after completing diet and exercise interventions: follow-up study for a single-blind, single-center, randomized controlled trial [with consumer summary] |
| Source: | Arthritis Care & Research 2022 Apr;74(4):607-616 |
| Method: | clinical trial |
| Method Score: | 5/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: No; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: Yes; Adequate follow-up: No; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed* |
| Consumer Summary: | SIGNIFICANCE AND INNOVATIONS: The normal trajectory for community-dwelling older adults with knee osteoarthritis (OA) is one of weight gain and a consistent knee pain profile. In contrast, older adults with knee OA who completed 1.5-year diet or diet plus exercise interventions experienced partial weight regain 3.5 years later, yet relative to baseline, they preserved statistically significant changes in weight loss and reductions in knee pain. Taken together, these results suggest that diet and/or exercise interventions are effective nonpharmacologic treatments for older adults with knee OA that can result in improved clinical outcomes > 3 years after the treatments end. These data imply that clinicians who treat patients with knee OA have a variety of nonpharmacologic options that preserve clinically important effects. |
| Abstract: | Copyright release for this abstract has not been granted. Abstract and full text (sometimes free) may be available at these link(s):  help |
