Detailed Search Results
| Author/Association: | Molenaar CJL, Minnella EM, Coca-Martinez M, Ten Cate DWG, Regis M, Awasthi R, Martinez-Palli G, Lopez-Baamonde M, Sebio-Garcia R, Feo CV, van Rooijen SJ, Schreinemakers JMJ, Bojesen RD, Gogenur I, van den Heuvel ER, Carli F, Slooter GD |
| Title: | Effect of multimodal prehabilitation on reducing postoperative complications and enhancing functional capacity following colorectal cancer surgery: the PREHAB randomized clinical trial [with consumer summary] |
| Source: | JAMA Surgery 2023 Jun;158(6):572-581 |
| Method: | clinical trial |
| Method Score: | 8/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: Yes; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: Yes; Adequate follow-up: Yes; Intention-to-treat analysis: Yes; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed* |
| Consumer Summary: | KEY POINTS: QUESTION: Does a 4-week supervised multimodal prehabilitation program before elective resection of nonmetastasized colorectal cancer reduce postoperative complications and enhance functional recovery. FINDINGS: In this multicenter, international randomized clinical trial that analyzed 251 adults, multimodal prehabilitation resulted in a significant reduction of severe and medical complications. The program also resulted in a statistically significant faster and better postoperative recovery. MEANING: Patients undergoing resection for nonmetastasized colorectal cancer may benefit from a 4-week multimodal prehabilitation program. |
| Abstract: | Copyright release for this abstract has not been granted. Abstract and full text (sometimes free) may be available at these link(s):  help |
