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Author/Association: Boyne P, Billinger SA, Reisman DS, Awosika OO, Buckley S, Burson J, Carl D, DeLange M, Doren S, Earnest M, Gerson M, Henry M, Horning A, Khoury JC, Kissela BM, Laughlin A, McCartney K, McQuaid T, Miller A, Moores A, Palmer JA, Sucharew H, Thompson ED, Wagner E, Ward J, Wasik EP, Whitaker AA, Wright H, Dunning K
Title: Optimal intensity and duration of walking rehabilitation in patients with chronic stroke: a randomized clinical trial [with consumer summary]
Source: JAMA Neurology 2023 Apr;80(4):342-351
Method: clinical trial
Method Score: 8/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: Yes; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: Yes; Adequate follow-up: Yes; Intention-to-treat analysis: Yes; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*
Consumer Summary: KEY POINTS: QUESTION: For walking exercise in patients with chronic stroke, what is the optimal intensity (vigorous vs moderate) and minimum duration (4, 8, or 12 weeks) to maximize immediate improvement in walking capacity? FINDINGS: In this randomized clinical trial that enrolled 55 stroke survivors, 6-minute walk test gains after 12 weeks of training were 71 m with vigorous training intensity vs 27 m with moderate training intensity, a significant difference. Within the vigorous intensity group, walking capacity significantly increased after each 4-week training block. MEANING: The findings suggest that optimal dosing for walking exercise for patients with chronic stroke may include at least 12 weeks of training at vigorous intensity.
Abstract: Copyright release for this abstract has not been granted.

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