Detailed Search Results
| Author/Association: | Nymand SB, Hartmann J, Rasmussen IE, Iepsen UW, Ried-Larsen M, Christensen RH, Berg RMG |
| Title: | Fidelity and tolerability of two high-intensity interval training protocols in patients with COPD: a randomised cross-over pilot study [with consumer summary] |
| Source: | BMJ Open Sport & Exercise Medicine 2023;9(1):e001486 |
| Method: | clinical trial |
| Method Score: | 5/10 [Eligibility criteria: No; Random allocation: Yes; Concealed allocation: Yes; Baseline comparability: No; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: Yes; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed* |
| Consumer Summary: | WHAT IS ALREADY KNOWN ON THIS TOPIC: High-intensity interval training (HIIT) is recommended as a training regimen for pulmonary rehabilitation in patients with chronic obstructive pulmonary disease (COPD). Many different protocols with differing intensities, number of intervals and work-to-rest ratios are currently used in COPD, but the fidelity and tolerability of these schemes has not previously been compared. WHAT THIS STUDY ADDS: A single HIIT session using long (4x4 HIIT) intervals at a relatively lower intensity has a higher fidelity than short (10x1 HIIT) intervals at a very high intensity in patients with moderate-to-severe COPD, while the two protocols appear to be similarly tolerated. HOW THIS STUDY MIGHT AFFECT RESEARCH, PRACTICE OR POLICY: In rehabilitation programmes and future clinical trials in patients with COPD, 4x4 HIIT protocols at a relatively lower intensity may lead to higher patient adherence and thus potentially greater clinical efficacy than 10x1 HIIT at a very high intensity. |
| Abstract: | OBJECTIVES: High-intensity interval training (HIIT) during pulmonary rehabilitation in patients with chronic obstructive pulmonary disease (COPD) may alleviate the symptom burden, but the fidelity and tolerability of HIIT using long or short intervals in patients with COPD are unknown. METHODS: Twelve patients with moderate-to-severe COPD were included in a randomised cross-over pilot study. They completed two supervised HIIT protocols (4x4 and 10x1). To compare the two HIIT protocols, completed training amount, exercise intensity and perceived tolerability (assessed by a 10-point Likert scale) were integrated in a red-amber-green rating system. If a training session received a red ranking, it was considered unacceptable, if it received an amber ranking it was applicable with precautions, and if it received a green ranking it was considered feasible. RESULTS: All patients completed the total training amount in both protocols. The 4x4 protocol resulted in three amber training sessions due to low perceived tolerability. The 10x1 protocol resulted in two red training sessions due to intensity reductions, and two amber training sessions because of low perceived tolerability. There was no statistical difference in perceived tolerability or time spent with an HR >= 85% of HRmax. CONCLUSIONS: HIIT using longer intervals (4x4) at a relatively lower intensity resulted in higher fidelity expressed by fewer adjustments to the protocol, whereas there was no difference between protocols in perceived tolerance. The 4x4 protocol seems to have a higher fidelity compared with the 10x1 protocol in patients with moderate-to-severe COPD. TRIAL REGISTRATION NUMBER: NCT05273684. Full text (sometimes free) may be available at these link(s):  help |
